The MiniMed Paradigm REAL-Time System is the world's first system that integrates an insulin pump with REAL-Time continuous glucose monitoring.

The first part of the system is the MiniMed Paradigm REAL-Time 522 or 722 insulin pump, built on the MiniMed Paradigm platform with all the features you expect from a "smart" insulin pump. Insulin pump therapy, with or without continuous glucose monitoring, gives you:

• Freedom from multiple daily injections
• Freedom to eat, sleep, and exercise when you want
• Better glucose control with less risk of going low

The second part of the system is the optional REAL-Time Continuous Glucose Monitoring component, which offers REAL-Time glucose readings, safety alarms, and glucose trend data.

Easy to Wear, Easy to Use

Part of the #1 prescribed MiniMed Paradigm family of insulin pumps, the MiniMed Paradigm 522 or 722 insulin pump is small so you can wear it almost anywhere – under your clothing in a leg pouch, thigh pouch, bra pouch, or on your belt like a cell phone. It delivers insulin through a soft tube called a cannula that sits under your skin for up to 3 days after being inserted in one virtually painless step. You can disconnect from the insulin pump easily and quickly for activities such as bathing, swimming, or changing clothes.

Continuous glucose monitoring is made possible through a tiny sensor you wear for up to three days at a time. Like the cannula, it is easily inserted using an automatic insertion device provided with the system. Sensor data is sent continuously to a transmitter, a small lightweight device that attaches to your skin with a small, simple, adhesive patch. The sensor, transmitter, and adhesive patch are all waterproof. The transmitter sends the data to the insulin pump through advanced radio frequency (RF) wireless technology.

REAL-Time Continuous Glucose Monitoring Lets You Enjoy REAL Control with REAL Confidence

REAL-Time Readings help you take action sooner to improve control of your glucose levels and reduce the risk of long-term health complications. The MiniMed Paradigm REAL-Time System takes measurements continuously and displays updated glucose values every five minutes to help you take the right action at the right time to improve control of your diabetes. Fingerstick measurements using a standard blood glucose meter are still required before making therapy adjustments, and to calibrate the system.

REAL-Time Alarms warn you of low and high glucose levels that fingersticks and A1C testing may miss. You can preset alarms to sound or vibrate. You can even customize the setting to just the right sensitivity for you.

REAL-Time Trend Arrows point up or down to clearly show you the direction and rate of change in your glucose. Because even brief fluctuations can increase your risk of long-term problems, this information helps you reduce the risk of long-term complications such as eye, nerve, heart, and kidney disease.

REAL-Time Trend Graphs show you the effect of meals, exercise, insulin, and medication on control of your glucose levels. Additionally, you can upload historical data from the insulin pump to CareLink® Online, where you can generate longer-term charts, graphs, and tables for your records or to share with your health care providers.

Who Can Use the MiniMed Paradigm REAL-Time System?

• The insulin pump is indicated for adults and children with type 1 and type 2 diabetes who require insulin.
• The REAL-Time glucose monitoring component is indicated for adults, age 18 and over, with type 1 and type 2 diabetes.

Choose the Components You Need

The MiniMed Paradigm 522 or 722 insulin pump can be purchased and used on its own. The REAL-Time continuous glucose monitoring kit is sold separately as a cash pay item (not covered by most insurance plans). Although the kit is not available until summer 2006, you can get started now through the Step It Up Program.